PHYTOCHEMICAL ANALYSIS AND INHIBITORY EFFECT OF PYRENACANTHA STAUDTII LEAF EXTRACT ON ISOLATED RAT UTERUS
Pyrenanacantha staudtii leaf is used ethnomedicinally in Nigeria and some African countries for the prevention of miscarriage (threatened abortion) in pregnant women. The study was therefore aimed at validating the claim by the traditional herbal practitioners. The crude methanolic extract was subjected to isolated rat uterine preparation in an organ bath with oxytocin and salbutamol as controls.Both oxytocin and the spontaneous contractions of the
uterus were recorded with an Ugo basil recorder.