The aim of this study is to determine the haematological values, haemoglobin A2 and F that can be used in monitoring the status and management of sickle cell anaemia (SCA) patients. Haematological values were determined in SCA with 200 patients (81.3%) in steady state and 46 patients (18.7%) in vaso-occlusive crisis (VOC) in three centers in Benin City, Nigeria as well as 84 control subjects. Automated Coulter Counter was used to determine the complete blood counts while the foetal haemoglobin was estimated by the modified Betke method and haemoglobin A2 by HbS-free microcolumn chromatography.

HAEMATOLOGICAL VALUES IN SICKLE CELL ANAEMIA IN STEADY STATE AND DURING VASO-OCCLUSIVE CRISIS IN BENIN CITY,